The results showed that at 7 days of bone repair, groups I and II had similar and statistically significant values of optical density while the other groups had similar values among themselves. ![]() All data collected were analysed by ANOVA and the Tukey´s Test (p?0.05). ![]() After 7 and 28 days of treatment, the animals were sacrificed and the tibias were removed for analysis of radiographic optical density by the digital system RVG Trophy and the Image Programme Tool 2.03®. 30 days after castration, a 3 mm bone defect was made in the right tibia of the animals. 50 animals were divided in 5 groups of 10: (I) SHAM, (II) Castrated rats, (III) Castrated rats treated with 1mg/kg/day risedronate, (IV) Castrated rats treated with 1mg/kg/day raloxifene and (V) Castrated rats treated with 3mg/kg/day raloxifene. The aim of this study was to analyse radiographically the effects of sodium risedronate (OSG Norwich Pharmaceticals, EUA) and raloxifene hydrochloride (Eli Lilly & Company Ltd ING.) in bone repair of male rats with osteopenia. ![]() Farmacoterapia de raloxifeno y de risedronato en el proceso de reparación ósea en ratones machos con osteopenia.
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